PUBLICATIONS

No.	Authors Journal, Book DOI	Title	Involved Partners	Year
162	J Vergalli, A Atzori, J Pajovic, E Dumont, G Malloci, M Masi, AV Vargiu, M Winterhalter, M Refregiers, JM Pages Communications Biology 3 (1), 1-12 DOI:10.1038/s42003-020-0929-x	The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux	JUB, AMU, SYN	2020 in review
161	J Wang, JD Prajapati, U Kleinekathöfer, M Winterhalter Chemical science DOI:10.26434/chemrxiv.12319307.v1	Dynamic Interaction of Norfloxacin to Magnesium Monitored by Bacterial Outer Membrane Nanopores	JUB	2020 in review
160	J Wang, R Terrasse, JA Bafna, L Benier, M Winterhalter Angewandte Chemie International Edition 2020 59(22): 8517–8521. DOI:10.1002/anie.201913618	Electrophysiological Characterization of Transport Across Outer-Membrane Channels from Gram-Negative Bacteria in Presence of Lipopolysaccharides	JUB	2020
159	J Wang, R Terrasse, JA Bafna, L Benier, M Winterhalter Angewandte Chemie 132 (22), 8595-8599 2020 DOI:10.1002/ange.201913618	Elektrophysiologische Charakterisierung des Transports von Antibiotika durch äußere Membrankanäle in Gram-negativen Bakterien in Gegenwart von Lipopolysacchariden	JUB	2020
158	JA Bafna, E Sans-Serramitjana, S Acosta-Gutierrez, IV Bodrenko, D Hörömpöli, A Berscheid, H Brötz-Oesterhelt, M Winterhalter, M Ceccarelli ACS Infectious Diseases 2020 6 1855-1865 DOI:10.1021/acsinfecdis.0c00102	Kanamycin uptake into Escherichia coli is facilitated by OmpF and OmpC porin channels located in the outer membrane	JUB, UNICA	2020
157	JA Bafna, S Pangeni, M Winterhalter, MA Aksoyoglu Biophys J 2020 Jun 2;118(11):2844-2852 DOI:10.1016/j.bpj.2020.04.011	Electroosmosis Dominates Electrophoresis of Antibiotic Transport Across the Outer Membrane Porin F	JUB	2020
156	J Vergalli, IV Bodrenko, M Masi, L Moynié, S Acosta-Gutiérrez, … Nat Rev Microbiol 18,164-176 (2020) DOI:10.1038/s41579-019-0294-2	Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria	JUB	2020
155	HK Tam, VN Malviya, WE Foong, A Herrmann, G Malloci, P Ruggerone, AV Vargiu, KM Pos Journal of molecular biology 432 (4), 861-877 DOI:10.1016/j.jmb.2019.12.025	Binding and transport of carboxylated drugs by the multidrug transporter AcrB	UNICA, GUF	2020
154	A Atzori, G Malloci, F Cardamone, A Bosin, AV Vargiu, P Ruggerone Int. J. Mol. Sci. 2020, 21(3), 860 DOI:10.3390/ijms21030860	Molecular Interactions of Carbapenem Antibiotics with the Multidrug Efflux Transporter AcrB of Escherichia coli	UNICA	2020
153	Muriel Masi, Mathias Winterhalter, Jean-Marie Pagès In: Springer, Series title: Subcellular Biochemistry, Book: Bacterial Cell Walls and Membranes, Editor Andreas Kuhn DOI:10.1007/978-3-030-18768-2	Outer membrane porins	AMU, JUB	2019
152	Mariano A. Scorciapino, Giuliano Malloci, Ilaria Serra, Stefan Milenkovic, Lucile Moynie, James H. Naismith, Eric Desarbre, Malcolm G. P. Page, Matteo Ceccarelli Biometals. 2019 Jan 11. DOI:10.1007/s10534-018-00166-0	Complexes formed by the siderophore-monosulfactam conjugate BAL30072 and their interaction with the outer membrane receptor PiuA of P. aeruginosa	UNICA, USTAN, BASILEA	2019
151	Vinaya Kumar Golla, Eulália Sans-Serramitjana, Karunakar Reddy Pothula, Lorraine Benier, Jayesh Arun Bafna, Mathias Winterhalter, Ulrich Kleinekathöfer Biophys. J. DOI:10.1016/j.bpj.2018.12.002	Fosfomycin permeation through the outer membrane porin OmpF	JUB	2019
150	Watcharin Chumjan; Mathias Winterhalter; Wipa Siginta BBA - Biomembranes DOI:10.1016/j.bbamem.2018.12.012	Effects of H-Bonds on Sugar Binding to Chitoporin from Vibrio harveyi	JUB	2019
149	Moynié L, Serra I, Scorciapino M, Oueis E, Page MG, Ceccarelli M, Naismith JH Elife. 2018 Dec 18;7. pii: e42270 DOI:10.7554/eLife.42270	Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogen Acinetobacter baumannii	USTAN, UNICA	2019
148	Wang J, Bafna J, Bhamidimarri SP, Winterhalter M. Angew Chem Int Ed Engl. 2019 Mar 26; 58(14): 4737-4741 DOI:10.1002/anie.201814489	Small molecule permeation across membrane channels: Chemical modification to quantify transport across OmpF	JUB	2019
147	Schuster, S.; Bohnert, J.A.; Vavra, M.; Rossen, J.W.; Kern, W.V. Molecules 2019, 24, 470 DOI:10.3390/molecules24030470	Proof of an Outer Membrane Target of the Efflux Inhibitor Phe-Arg-ß-Naphthylamide from Random Mutagenesis	UKL-FR	2019
146	Cama J, Henney AM, Winterhalter M J Mol Biol. 2019. DOI:10.1016/j.jmb.2019.03.031	Breaching the Barrier: Quantifying Antibiotic Permeability across Gram-Negative Bacterial Membranes	JUB	2019
145	Bhamidimarri SP, Zahn M, Prajapati JD, Schleberger C, Söderholm S, Hoover J, West J, Kleinekathöfer U, Bumann D, Winterhalter M, van den Berg B. Structure. 2019 Feb 5;27(2):268-280.e6. DOI:10.1016/j.str.2018.10.021	A Multidisciplinary Approach toward Identification of Antibiotic Scaffolds for Acinetobacter baumannii	JUB, NEW, UNIBAS, GSK	2019
144	Igor V. Bodrenko, Samuele Salis, Silvia Acosta-Gutierrez, and Matteo Ceccarelli J. Chem. Phys. 150, 211102 (2019) DOI:10.1063/1.5098868	Diffusion of large particles through small pores: From entropic to enthalpic transport	UNICA	2019
143	Anne Davin-Regli, Jean-Philippe Lavigne, Jean-Marie Pagès Clin Microbiol Rev 32:e00002-19 DOI:10.1128/CMR.00002-19	Enterobacter spp.: Update on Taxonomy, Clinical Aspects, and Emerging Antimicrobial Resistance	AMU	2019
142	Schuster S, Vavra M, Kern WV Antimicrob Agents Chemother 63:e01041-19 DOI:10.1128/AAC.01041-19	Efflux-mediated resistance to new oxazolidinones and pleuromutilin derivatives in Escherichia coli with class specificities in the resistance-nodulation-cell division-type drug transport pathways	UKL-FR	2019
141	Lucile Moynié, Stefan Milenkovic, Gaëtan L.A. Mislin, Véronique Gasser, Giuliano Malloci, Etienne Baco, Rory P. McCaughan, Malcolm G.P. Page, Isabelle J. Schalk, Matteo Ceccarelli & James H. Naismith Nature Communications 10, 3673–14 DOI:10.1038/s41467-019-11508-y	The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model	USTAN, CNRS, UNICA, JUB	2019
140	J Wang, JA Bafna, SP Bhamidimarri, M Winterhalter Angewandte Chemie, 2019, 131 4788-4792 DOI:10.1002/ange.201814489	Permeation von kleinen Molekülen durch Membrankanäle: Chemische Modifikation zur Quantifizierung des Transports über OmpF*	JUB	2019
139	J Coines, S Acosta-Gutierrez, I Bodrenko, C Rovira, M Ceccarelli Phys. Chem. Chem. Phys. 21 (16), 8457-8463 DOI:10.1039/C9CP00778D	Glucose transport via the pseudomonad porin OprB: implications for the design of Trojan Horse anti-infectives	JUB, UNICA	2019
138	A Atzori, G Malloci, JD Prajapati, A Basciu, A Bosin, U Kleinekatho¨fer, J Dreier, AV Vargiu, P Ruggerone J. Phys. Chem. B 2019 123 (22), 4625-4635 DOI:10.1021/acs.jpcb.9b01351	Molecular interactions of cephalosporins with the deep binding pocket of the RND transporter AcrB	JUB	2019
137	A Kesireddy, KR Pothula, J Lee, DS Patel, M Pathania, B van den Berg, W Im, U Kleinekathöfer J. Phys. Chem. B 2019 123 (27), 5700-5708 DOI:10.1021/acs.jpcb.9b03669	Modeling of specific lipopolysaccharide binding sites on a Gram-negative porin	JUB	2019
136	Cunrath O, Meinel DM, Maturana P, Fanous J, Buyck JM, Saint Auguste P, Seth-Smith HMB, Körner J, Dehio C, Trebosc V, Kemmer C, Neher R, Egli A, Bumann D.EBioMedicine. 2019 Mar;41:479-487. DOI:10.1016/j.ebiom.2019.02.061	Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains.	UNIBAS	2019
135	Dumont E, Vergalli J, Pajovic J, Bhamidimarri SP, Morante K, Wang J, Lubriks D, Suna E, Stavenger RA, Winterhalter M, Réfrégiers M, Pagès JM. Life Science Alliance 2018 Dec 28;2(1):e201800242 DOI:10.26508/lsa.201800242	Mechanistic aspects of maltotriose-conjugate translocation to the Gram-negative bacteria cytoplasm	AMU, SYN, JUB, GSK, NEW	2018
134	Jiajun Wang, Lorraine Benier, Mathias Winterhalter ACS Omega, 2018, 3 (12), pp 17481–17486 DOI:10.1021/acsomega.8b01611	Quantifying permeation of small charged molecules across channels: electrophysiology in small volumes	JUB	2018
133	Dumont E, Vergalli J, Conraux L, Tailler C, Pajovic J, Vassort A, Réfrégiers M, Mourez M, Pagès JM J Antimicrob Chemother DOI:10.1093/jac/dky396	Antibiotic and efflux: Combined spectrofluorimetry and mass spectrometry to evaluate the involvement of concentration and efflux activity in antibiotic intracellular accumulation	AMU, SANOFI, SYN	2018
132	Atzori A, Malviya V, Malloci G, Dreier J, Pos KM, Vargiu AV, Ruggerone P Biochim Biophys Acta - Biomembranes DOI:10.1016/j.bbamem.2018.10.012	Identification and characterization of carbapenem binding sites within the RND-transporter AcrB	UNICA, BASILEA, GUF	2018
131	Matthew P. McCusker, Daniela Alves Ferreira, Donal Cooney, Bruno Martins Alves, Seámus Fanning, Jean-Marie Pagès, Marta Martins, Anne Davin-Regli. Global Antimicrobial Resistance DOI:10.1016/j.jgar.2018.10.009	Modulation of antibiotic resistance in clinical isolates of Enterobacter aerogenes - a strategy combining antibiotics and chemosensitiser	AMU, UCD	2018
130	Terrasse R, Winterhalter M. M. Eur. Phys. J. E, 41: 111. DOI:10.1140/epje/i2018-11721-9	Translocation of small molecules through engineered outer-membrane channels from Gram-negative bacteria	JUB	2018
129	Bodrenko I, Salis S, Acosta-Gutierrez S, Ceccarelli M Physical Review Letter arXiv preprint arXiv:1805,12541	Diffusion of large particles through small pores: from entropic to enthalpic transport	UNICA	2018
128	Heng-Keat Tam, Viveka Nand Malviya and Klaas M. Pos In: Yamaguchi A., Nishino K. (eds) Bacterial Multidrug Exporters. Methods in Molecular Biology, vol 1700. Humana Press, New York, NY DOI:10.1007/978-1-4939-7454-2_1	High resolution crystallographic analysis of AcrB using Designed Ankyrin Repeat Proteins (DARPins)	GUF	2018
127	Cacciotto P, Ramaswamy VK, Malloci G, Ruggerone P, Vargiu AV In: Yamaguchi A., Nishino K. (eds) Bacterial Multidrug Exporters. Methods in Molecular Biology, vol 1700. Humana Press, New York, NY DOI:10.1007/978-1-4939-7454-2_11	Molecular modeling of multi-drug properties of Resistance Nodulation Division (RND) transporters	UNICA	2018
126	Vargiu AVV, Ramaswamy VK, Malvacio I, Malloci G, Kleinekathöfer U, Ruggerone P Biochimica et Biophysica Acta (BBA) - General Subjects, Volume 1862, Issue 4, Pages 836-845, ISSN 0304-4165 DOI:10.1016/j.bbagen.2018.01.010	Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump	UNICA, JUB	2018
125	Citak F, Ghai I, Rosenkötter F, Benier L, Winterhalter M, Wagner R Biochem Biophys Res Commun 495(1): 1454-1460 DOI:10.1016/j.bbrc.2017.11.188	Probing transport of fosfomycin through substrate specific OprO and OprP from Pseudomonas aeruginosa	JUB, ION	2018
124	Ganguly S, Kesireddy A, Barcena-Uribarri I, Kleinekathöfer U, Benz R Biophys J 113(4): 829-834 DOI:10.1016/j.bpj.2017.07.004	Conversion of OprO into an OprP-like Channel by Exchanging Key Residues in the Channel Constriction	JUB	2018
123	Schalk IJ Clin Microbiol Infect 24(8): 801-802 DOI:10.1016/j.cmi.2018.03.037	Siderophore-antibiotic conjugates: exploiting iron uptake to deliver drugs into bacteria	CNRS	2018
122	Zomot E, Yardeni EH, Vargiu AV, Tam HK, Malloci G, Ramaswamy VK, Perach M, Ruggerone P, Pos KM, Bibi E J Mol Biol 430(9): 1368-1385 DOI:10.1016/j.jmb.2018.02.026	A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter	UNICA	2018
121	Masi M, Dumont E, Vergalli J, Pajovic J, Réfrégiers M, Pagès JM. Res Microbiol. 2017 Dec 5. pii: S0923-2508(17)30197-3. DOI:10.1016/j.resmic.2017.11.005	Fluorescence enlightens RND pump activity and the intrabacterial concentration of antibiotics	AMU, SYN	2018
120	Vargiu AV, Ramaswamy VK, Malloci G, Malvacio I, Atzori A, Ruggerone P Res Microbiol, 169 (7-8), 384-392 DOI:10.1016/j.resmic.2017.12.001	Computer simulations of the activity of RND efflux pumps	UNICA	2018
119	Bolam DN, van den Berg B Curr Opin Struct Biol 51: 35-43 DOI:10.1016/j.sbi.2018.03.001	TonB-dependent transport by the gut microbiota: novel aspects of an old problem	NEW	2018
118	Pathania M, Acosta-Gutierrez S, Bhamidimarri SP, Baslé A, Winterhalter M, Ceccarelli M, van den Berg B Structure. 2018 May 1;26(5):708-721.e4. Epub 2018 DOI:10.1016/j.str.2018.03.010	Unusual Constriction Zones in the Major Porins OmpU and OmpT from Vibrio cholerae	JUB, UNICA, NEW	2018
117	Prajapati JD, Fernández Solano CJ, Winterhalter M, Kleinekathöfer U. J Phys Chem B. 2018 Jan 6. DOI:10.1021/acs.jpcb.7b12568	Enrofloxacin Permeation Pathways across the Porin OmpC.	JUB	2018
116	Lee J, Pothula KR, Kleinekathöfer U, Im W J Phys Chem B, in press DOI:10.1021/acs.jpcb.8b07109	Simulation Study of Occk5 Functional Properties in Pseudomonas aeruginosa Outer Membranes	JUB	2018
115	Perraud Q, Moynie L, Gasser V, Munier M, Godet J, Hoegy F, Mely Y, Mislin GLA, Naismith JH, Schalk IJ ACS Chem Biol, in print DOI:10.1021/acschembio.8b00543	A key role for the periplasmic PfeE esterase in iron acquisition via the siderophore Enterobactin in Pseudomonas aeruginosa	CNRS, USTAN	2018
114	Acosta-Gutierrez S, Ferrara L, Pathania M, Masi M, Wang J, Bodrenko I, Zahn M, Winterhalter M, Stavenger RA, Pages JM, Naismith JH, van den Berg B, Page M, Ceccarelli M. ACS Infect Dis. 2018 Jul 2. DOI:10.1021/acsinfecdis.8b00108	Getting drugs into Gram-negative bacteria: Rational rules for permeation through general porins.	JUB, GSK, AMU, USTAN, NEW, UNICA, BASILEA	2018
113	Samanta S, Bodrenko I, Acosta-Gutierrez S, D'Agostino T, Pathania M, Ghai I, Schleberger C, Bumann D, Wagner R, Winterhalter M, van den Berg B, Ceccarelli M ACS Infect Dis. 2018 Jul 24 DOI:10.1021/acsinfecdis.8b00149	Getting drugs through small pores: exploiting the porins pathway in Pseudomonas aeruginosa	UNICA, JUB, NEW, UNIBAS, ION	2018
112	Julia Vergalli, Estelle Dumont, Jelena Pajovic´, Bertrand Cinquin, Laure Maigre, Muriel Masi, Matthieu Réfrégiers & Jean-Marie Pagès nature protocols, VOL.13, NO.6 DOI:10.1038/nprot.2018.036	Spectrofluorimetric quantification of antibiotic drug concentration in bacterial cells for the characterization of translocation across bacterial membranes	AMU, SYN	2018
111	Anuwat Aunkham, Michael Zahn, Anusha Kesireddy, Karunakar Reddy Pothula, Albert Schulte, Arnaud Baslé, Ulrich Kleinekathöfer, Wipa Suginta & Bert van den Berg Nature Communications 9, Article number: 220(2018) DOI:10.1038/s41467-017-02523-y	Structural basis for chitin acquisition by marine Vibrio species	JUB, NEW	2018
110	Du D, Wang-Kan X, Neuberger A, van Veen HW, Pos KM, Piddock LJV, Luisi BF Nat Rev Microbiol 16(9): 523-539 DOI:10.1038/s41579-018-0048-6	Multidrug efflux pumps: structure, function and regulation	GUF	2018
109	Benkerrou D, Ceccarelli M Phys. Chem. Chem. Phys DOI:10.1039/c7cp08299a	Free energy calculations and molecular properties of substrate translocation through OccAB porins	UNICA	2018
108	Ghai I, Bajaj H, Bafna JA, Damrany HAE, Winterhalter M, Wagner R J Biol Chem DOI:10.1074/jbc.ra117.000705	Ampicillin permeation across OmpF, the major outer membrane channel in E. coli	JUB, ION	2018
107	Ando T, Bhamidimarri SP, et al. J. Phys. D: Appl. Phys, 116140 DOI:10.1088/1361-6463	The 2018 Correlative Microscopy Techniques Roadmap	JUB	2018
106	Molitor A, James CE, Fanning S, Pagès JM, Davin-Regli A. J Med Microbiol. 2018 Jan 3. DOI:10.1099/jmm.0.000667	Ram locus is a key regulator to trigger multidrug resistance in Enterobacter aerogenes	AMU, UCD	2018
105	Luscher A, Moynié L, Saint Auguste P, Bumann D, Mazza L, Pletzer D, Naismith JH, Köhler T. Antimicrob Agents Chemother. 2018 Mar 19. pii: AAC.00097-18. DOI:10.1128/aac.00097-18	The TonB-receptor repertoire of Pseudomonas aeruginosa for the uptake of siderophore-drug conjugates	USTAN, UNIBAS, JUB, UGE	2018
104	Abdali N, Younas F, Mafakheri S, Pothula KR, Kleinekathöfer U, Tauch A, Benz R BMC Biochem 19(1): 3 DOI:10.1186/s12858-018-0093-9	Identification and characterization of smallest pore-forming protein in the cell wall of pathogenic Corynebacterium urealyticum DSM 7109	JUB	2018
103	Lome V, Brunel JM, Pagès J-M, Bolla JM. Front Microbiol 9:204 DOI:10.3389/fmicb.2018.00204	Multiparametric Profiling for Identification of Chemosensitizers against Gram-Negative Bacteria	AMU	2018
102	Ferrer-Navarro M, Strehlitz A, Medina E, Vila J Front. Microbiol 9: 928 DOI:10.3389/fmicb.2018.00928	Changed Expression of Cytoskeleton Proteins During Lung Injury in a Mouse Model of Streptococcus pneumoniae Infection	CRESIB	2018
101	Ramaswamy VK, Vargiu AV, Malloci G, Dreier J, Ruggerone P Front Microbiol 9: 1144 DOI:10.3389/fmicb.2018.01144	Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa	UNICA	2018
100	Marie-Helene Nicolas-Chanoine, Noemie Mayer, Kathleen Guyot, Estelle Dumont, Jean-Marie Pagès Front Microbiol 9: 1422 DOI:10.3389/fmicb.2018.01422	Interplay between membrane permeability and enzymatic barrier leads to antibiotic-dependent resistance in Klebsiella pneumoniae	AMU, APHP-BUH	2018
99	Hans Prochnow, Verena Fetz, Sven-Kevin Hotop, Mariel A. García-Rivera, Axel Heumann, and Mark Brönstrup Anal. Chem., Article ASAP DOI:10.1021/acs.analchem.8b03586	Subcellular Quantification of Uptake in Gram-Negative Bacteria	JUB	2018
98	Tanzir Ahmed, Sander van den Driesche, Martin Oellers, Roland Hemmler, Karsten Gall, Satya Prathyusha Bhamidimarri, Mathias Winterhalter, Richard Wagner, Michael J. Vellekoop Multidisciplinary Digital Publishing Institute Proceedings 2 ( 2018), 920 DOI:10.3390/proceedings2130920	Fast Formation of Lipid Bilayer Membranes for Simultaneous Analysis of Molecular Transport Using Parylene Coated Chips	JUB, ION	2018
97	Alessia Gilardi; Satya P Bhamidimarri; Mark Brönstrup; Ursula Bilitewski; Ravi K Marreddy; Klaas M Pos; Lorraine Benier; Philip Gribbon; Mathias Winterhalter; Björn Windshügel Biochimica et Biophysica Acta (BBA) - General Subjects DOI:10.1016/j.bbagen.2017.07.014	Biophysical characterization of E. coli TolC interaction with the known blocker hexaamminecobalt	IME-SP, JUB, GUF	2017
96	Ishan Ghai, Mathias Winterhalter, Richard Wagner Biochemical and Biophysical Research Communications. Volume 484, Issue 1, 26 February 2017, Pages 51–55 DOI:10.1016/j.bbrc.2017.01.076	Probing transport of charged ß-lactamase inhibitors through OmpC, a membrane channel from E. coli	JUB, ION	2017
95	Naresh Niranjan Dhanasekar, Soumeya Aliouane, Mathias Winterhalter, Jean-Marie Pagès, Jean-Michel Bolla Biochemistry and Biophysics Reports DOI:10.1016/j.bbrep.2017.06.007	Peptide translocation across MOMP, the major outer membrane channel from Campylobacter jejuni	JUB, AMU	2017
94	Paulen A, Hoegy F, Roche B, Schalk IJ, Mislin GLA Bioorg Med Chem Lett. 2017 Nov 1;27(21):4867-4870 DOI:10.1016/j.bmcl.2017.09.039	Synthesis of conjugates between oxazolidinone antibiotics and a pyochelin analogue	CNRS	2017
93	Giuliano Malloci, Giovanni Serra, Andrea Bosin, Attilio Vittorio Vargiu, Paolo Ruggerone Biophysical Journal Volume 112, Issue 3, Supplement 1, 3 February 2017, Pages 493a–494a DOI:10.1016/j.bpj.2016.11.2671	Binding of Antibiotics to the Multidrug Efflux Pump AcrB of E. coli Investigated by Molecular Docking	UNICA	2017
92	Schuster S, Vavra M, Schweigger TM, Rossen JWA, Matsumura Y, Kern WV Int J Antimicrob Agents. 2017 Jul 6. pii: S0924-8579(17)30252-2. DOI:10.1016/j.ijantimicag.2017.03.023	Contribution of AcrAB-TolC to multidrug resistance in an Escherichia coli sequence type 131 isolate	UKL-FR	2017
91	Que-Tien Tran, Laure Maigre, Tommaso D'Agostino, Matteo Ceccarelli, Mathias Winterhalter, Jean-Marie Pagès, Anne Davin-Regli Res Microbiol. 2017 May 30. pii: S0923-2508(17)30111-0 DOI:10.1016/j.resmic.2017.05.003	Porin flexibility in Providencia stuartii: cell-surface-exposed loops L5 and L7 are markers of Providencia porin OmpPst1	JUB, UNICA, AMU	2017
90	Prajapati JD, Fernández Solano CJ, Winterhalter M, Kleinekathöfer U. J Chem Theory Comput. 2017 Aug 17. DOI:10.1021/acs.jctc.7b00467	Characterization of Ciprofloxacin Permeation Pathways across the Porin OmpC using Metadynamics and a String Method	JUB	2017
89	Pothula, Karunakar; Dhanasekar, Naresh; Lamichhane, Usha; Younas, Farhan; Pletzer, Daniel; Benz, Roland; Winterhalter, Mathias; Kleinekathöfer, Ulrich J. Phys. Chem. B, 2017, 121 (12), pp 2614–2621 DOI:10.1021/acs.jpcb.7b01787	A Single Residue Acts as Gate in OccK Channels	JUB	2017
88	Ghai, Ishan; Pira, Alessandro; Scorciapino, Mariano; Bodrenko, Igor; Benier, Lorraine; Ceccarelli, Matteo; Winterhalter, Mathias; Wagner, Richard The Journal of Physical Chemistry Letters DOI:10.1021/acs.jpclett.7b00062	A General Method to Determine the Flux of Charged Molecules Through Nanopores Applied to ß-Lactamase Inhibitors and OmpF	JUB, UNICA, ION	2017
87	Neveshkin, Alexander; Citak, Funda; Ball, Vincent; Winterhalter, Mathias Langmuir. 2017 Jul 25;33(29):7256-7262 DOI:10.1021/acs.langmuir.7b01959	Polydopamine coating to stabilize free standing lipid bilayer for channel sensing	JUB	2017
86	Soundararajan G, Bhamidimarri SP, Winterhalter M. ACS Chem Biol. 2017 Jun 16;12(6):1656-1664 DOI:10.1021/acschembio.6b01150	Understanding carbapenem translocation through OccD3 (OpdP) of Pseudomonas aeruginosa.	JUB	2017
85	Bajaj H, Acosta Gutierrez S, Bodrenko I, Malloci G, Scorciapino MA, Winterhalter M, Ceccarelli M. ACS Nano. 2017 11:5465-5473 DOI:10.1021/acsnano.6b08613	Bacterial Outer Membrane Porins as Electrostatic Nanosieves: Exploring Transport Rules of Small Polar Molecules	UNICA, JUB	2017
84	Bodrenko, Igor; Wang, Jiajun; Salis, Samuele; Winterhalter, Mathias; Ceccarelli, Matteo ACS Sens. 2017 Aug 25;2(8):1184-1190. DOI:10.1021/acssensors.7b00311	Sensing Single Molecule Penetration into Nanopores: Pushing the Time Resolution to the Diffusion Limit	UNICA, NAN, JUB	2017
83	Glenwright AJ, Pothula KR, Bhamidimarri SP, Chorev DS, Baslé A, Firbank SJ, Zheng H, Robinson CV, Winterhalter M, Kleinekathöfer U, Bolam DN, van den Berg B. Nature DOI:10.1038/nature20828	Structural basis for nutrient acquisition by dominant members of the human gut microbiota.	JUB, NEW	2017
82	Muriel Masi, Matthieu Refregiers, Klaas M. Pos, Jean-Marie Pages Nature Microbiology DOI:10.1038/nmicrobiol.2017.1	Mechanisms of envelope permeability and antibiotic efflux in Gram-negative bacteria	AMU, SYN, GUF	2017
81	Abellón-Ruiz J, Kaptan SS, Baslé A, Claudi B, Bumann D, Kleinekathöfer U, van den Berg B. Nat Microbiol. 2017 Oct 16. DOI:10.1038/s41564-017-0046-x	Structural basis for maintenance of bacterial outer membrane lipid asymmetry	NEW, UNIBAS, JUB	2017
80	A. Allam, L. Maigre, J. Vergalli, E. Dumont, B. Cinquin, R. Alves de Souza, E. Pinet, N. Smith, J-P. Herbeuval, M. Réfregiers, I. Artaud, J-M. Pagès Scientific Reports 7, Article number: 986 DOI:10.1038/s41598-017-00945-8	Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria	AMU, SYN	2017
79	Bialek-Davenet S, Mayer N, Vergalli J, Duprilot M, Brisse S, Pagès JM, Nicolas-Chanoine MH Sci Rep. 2017 Jul 27;7(1):6722. DOI:10.1038/s41598-017-06503-6	In-vivo loss of carbapenem resistance by extensively drug-resistant Klebsiella pneumoniae during treatment via porin expression modification	AMU, APHP-BUH	2017
78	Ramaswamy, V. K., Vargiu, A. V., Malloci, G., Dreier, J., & Ruggerone, P. Sci Rep 7(1): 8075 DOI:10.1038/s41598-017-08747-8	Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters	BASILEA, UNICA	2017
77	Vergalli J, Dumont E, Cinquin B, Maigre L, Pajovic J, Bacqué E, Mourez M, Réfregiers M, Pagès J-M Sci. Reports 7: 9821 DOI:10.1038/s41598-017-08775-4	Fluoroquinolone structure and translocation flux across bacterial membrane	AMU, SYN, SARD	2017
76	Ramaswamy, V. K., Cacciotto, P., Malloci, G., Vargiu, A. V., & Ruggerone, P. Essays in Biochemistry, 61(1), 141–156 DOI:10.1042/ebc20160065	Computational modelling of efflux pumps and their inhibitors	UNICA	2017
75	Pagès J-M Biol Aujourdhui 211(2): 149-154 DOI:10.1051/jbio/2017020	Antibiotic transport and membrane permeability: new insights to fight bacterial resistance	AMU	2017
74	Mariano Andrea Scorciapino, Silvia Acosta-Gutierrez, Dehbia Benkerrou, Tommaso D’Agostino, Giuliano Malloci, Susruta Samanta, Igor Bodrenko, Matteo Ceccarelli Journal of Physics: Condensed Matter 1–16 DOI:10.1088/1361-648x/aa543b	Rationalizing the permeation of polar antibiotics into Gram-negative bacteria	UNICA	2017
73	Moynie L, Luscher A, Rolo D, Pletzer D, Tortajada A, Weingart H, Braun Y, Page MG, Naismith JH, Köhler T Antimicrob Agents Chemother 61(4): e02531-16 DOI:10.1128/aac.02531-16	Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii	USTAN, JUB, BASILEA, UGE, UNIBAS, NEW	2017
72	Wu A, Tymoszuk P, Haschka D, Heeke S, Dichtl S, Petzer V, Seifert M, Hilbe R, Sopper S, Talasz H, Bumann D, Lass-Flörl C, Theurl I, Zhang K, Weiss G Infect Immun 85: e00418-17 DOI:10.1128/iai.00418-17	Salmonella utilizes zinc to subvert anti-microbial host defense of macrophages via modulation of NF-kB signaling	UNIBAS, NAN	2017
71	Davin-Regli A, Masi M, Bialek S, Nicolas-Chanoine MH, Pagès JM In: Li XZ., Elkins C., Zgurskaya H. (eds) Efflux-Mediated Antimicrobial Resistance in Bacteria (Adis, Cham), 281-306 DOI:10.1007/978-3-319-39658-3_11	Antimicrobial Drug Efflux Pumps in Enterobacter and Klebsiella	AMU	2016
70	Ramaswamy VK, Cacciotto P, Malloci G, Ruggerone P, Vargiu AV. In: Li XZ., Elkins C., Zgurskaya H. (eds) Efflux-Mediated Antimicrobial Resistance in Bacteria (Adis, Cham), 797-831. DOI:10.1007/978-3-319-39658-3_30	Multidrug Efflux Pumps and Their Inhibitors Characterized by Computational Modeling	UNICA	2016
69	Pletzer D, Braun Y, Weingart H. A. van Leeuwenhoek. 2016 109(6):737-53. DOI:10.1007/s10482-016-0675-8	Swarming motility is modulated by expression of the putative xenosiderophore transporter SppR-SppABCD in Pseudomonas aeruginosa PA14.	JUB	2016
68	K. R. Pothula, C. J. Solano and U. Kleinekathöfer Biochimica et Biophysica Acta (BBA) – Biomembranes DOI:10.1016/j.bbamem.2015.12.020	Simulations of outer membrane channels and their permeability	JUB	2016
67	Tommaso D’Agostino, Samuele Salis, and Matteo Ceccarelli BBA-Biomembranes 2016 DOI:10.1016/j.bbamem.2016.01.004	A Kinetic Model for Molecular Diffusion through Pores	UNICA	2016
66	Kinana AD, Vargiu AV, Nikaido H Biochem Biophys Res Commun 480(4): 552-557 DOI:10.1016/j.bbrc.2016.10.083	Effect of site-directed mutations in multidrug efflux pump AcrB examined by quantitative efflux assays	UNICA	2016
65	P. Bhamidimarri, J. D. Prajapati, B. van den Berg, M. Winterhalter and U. Kleinekathöfer Biophys. J. 110, 600–611 DOI:10.1016/j.bpj.2015.12.027	Role of Electroosmosis in the Permeation of Neutral Molecules: CymA and Cyclodextrin as an Example	JUB, NEW	2016
64	Allam A, Maigre L, Alves de Sousa R, Dumont E, Vergalli J, Pagès J-M, Artaud I. Eur J Med Chem. 2016 Oct 25. pii: S0223-5234(16)30916-3. DOI:10.1016/j.ejmech.2016.10.054	New amphiphilic neamine conjugates bearing a metal binding motif active against MDR E. aerogenes Gram-negative bacteria	AMU, SYN	2016
63	I Lytvynenko, S Brill, C Oswald, KM Pos J Mol Biol, Volume 428, Issue 3, 644–657 DOI:10.1016/j.jmb.2015.12.006	Molecular basis of polyspecificity of the Small Multidrug Resistance Efflux Pump AbeS from Acinetobacter baumannii	GUF	2016
62	Luana G M Ferrara, Gregor D Wallat, Lucile Moynié, Naresh Niranjan Dhanasekar, Mathias Winterhalter, Jean-Michel Bolla, Soumeya Aliouane, Jean-Marie Pagès, Silvia Acosta-Gutiérrez, Matteo Ceccarelli, James H Naismith Journal of Molecular Biology 428, no. 22 (November 6, 2016): 4528–43. DOI:10.1016/j.jmb.2016.09.021	MOMP From Campylobacter Jejuni Is a Trimer of 18-Stranded ß-Barrel Monomers with a Ca(2+) Ion Bound at the Constriction Zone.	NEW, JUB, AMU, UNICA	2016
61	Ferrer-Navarro M, Balleste-Delpierre C, Vila J, Fabrega A J Proteomics 146: 141-7 DOI:10.1016/j.jprot.2016.06.032	Characterization of the outer membrane subproteome of the virulent strain Salmonella Typhimurium SL1344	CRESIB	2016
60	Zahn M, Bhamidimarri SP, Baslé A, Winterhalter M, van den Berg B. Structure. (2016) 24:221-31 DOI:10.1016/j.str.2015.12.009	Structural Insights into Outer Membrane Permeability of Acinetobacter baumannii	NEW, JUB	2016
59	Solano CJF, Pothula KR, Prajapati JD, De Biase PM, Noskov SY, Kleinekathöfer U J Chem Theory Comput 12(5): 2401-17 DOI:10.1021/acs.jctc.5b01196	BROMOCEA Code: An Improved Grand Canonical Monte Carlo/Brownian Dynamics Algorithm Including Explicit Atoms	JUB	2016
58	Daury L, Orange F, Taveau JC, Verchère A, Monlezun L, Gounou C, Marreddy RK, Picard M, Broutin I, Pos KM, Lambert O Nat Commun 7: 10731 DOI:10.1038/ncomms10731	Tripartite assembly of RND multidrug efflux pumps	GUF	2016
57	Oswald, C., Tam, H-K., Pos, K. M. Nat. Commun. 7: 13819 DOI:10.1038/ncomms13819	Transport of lipophilic carboxylates is mediated by transmembrane helix 2 in multidrug transporter AcrB	GUF	2016
56	Acosta Gutierrez S, Bodrenko I, Scorciapino MA, Ceccarelli M Phys Chem Chem Phys 18(13): 8855-64 DOI:10.1039/c5cp07902k	Macroscopic electric field inside water-filled biological nanopores	UNICA	2016
55	Kinana AD, Vargiu AV, May T, Nikaido H Proc Natl Acad Sci USA 113(5): 1405-10 DOI:10.1073/pnas.1525143113	Aminoacyl ß-naphthylamides as substrates and modulators of AcrB multidrug efflux pump	UNICA	2016
54	Arunmanee W, Pathania M, Solovyova AS, Le Brun AP, Ridley H, Basle A, van den Berg B, Lakey JH Proc Natl Acad Sci U S A 113(34): E5034-43 DOI:10.1073/pnas.1602382113	Gram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesis	NEW	2016
53	Sjuts H, Vargiu AV, Kwasny SM, Nguyen ST, Kim HS, Ding X, Ornik AR1, Ruggerone P, Bowlin TL, Nikaido H, Pos KM, Opperman TJ Proc Natl Acad Sci USA 113(13): 3509-14 DOI:10.1073/pnas.1602472113	Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives	UNICA, GUF	2016
52	Harsha Bajaj, Mariano A. Scorciapino, Lucile Moynie, Malcolm G. P. Page, James H. Naismith, Matteo Ceccarelli, and Mathias Winterhalter J. Biol. Chem. 291 (2016) 2837-47 DOI:10.1074/jbc.m115.690156	Molecular Basis of Filtering Carbapenems by Porins from ß-Lactam-resistant Clinical Strains of Escherichia coli	JUB, UNICA, USTAN, BASILEA	2016
51	Kostyanev, T; Bonten, M; O'Brien, S; Steel, H; Ross, S; François, B; Tacconelli, E; Winterhalter, M; Stavenger, R; Karlén, A; Harbarth, S; Hackett, J; Jafri, H; Cuong, V; MacGowan, A; Witschi, A; Angyalosi, G; Elborn, S; deWinter, R; Goossens, H J. Antimicrob. Chemother. 71 (2): 290-295 DOI:10.1093/jac/dkv339	The Innovative Medicines Initiative's New Drugs for Bad Bugs programme – European public-private partnerships for the development of new strategies to tackle antibiotic resistance	GSK, JUB	2016
50	Gasser V, Baco E, Cunrath O, August PS, Perraud Q, Zill N, Schleberger C, Schmidt A, Paulen A, Bumann D, Mislin GL, Schalk IJ. Environ Microbiol. 2016 Mar;18(3):819-32. DOI:10.1111/1462-2920.13199	Catechol siderophores repress the pyochelin pathway and activate the enterobactin pathway in Pseudomonas aeruginosa: an opportunity for siderophore-antibiotic conjugates development	CNRS, UNIBAS	2016
49	Schuster S, Vavra M, Kern W Antimicrob Agent Chemother DOI:10.1128/aac.00314-16	Evidence of a substrate discriminating entrance channel in the lower porter domain of the multidrug resistance efflux pump AcrB	UKL-FR	2016
48	Bohnert JA, Schuster S, Kern WV, Karcz T, Olejarz A, Kaczor A, Handzlik J, Kiec-Kononowicz K Antimicrob Agents Chemother 60(4): 1974-83 DOI:10.1128/aac.01995-15	Novel Piperazine Arylideneimidazolones Inhibit the AcrAB-TolC Pump in Escherichia coli and Simultaneously Act as Fluorescent Membrane Probes in a Combined Real-Time Influx and Efflux Assay	UKL-FR	2016
47	Charles Auffray, Rudi Balling, Inês Barroso, et.al. Genome Medicine 20168:71 DOI:10.1186/s13073-016-0323-y	Making sense of big data in health research: Towards a European Union action plan	IME-SP	2016
46	Vargiu AV, Pos KM, Poole K, Nikaido H Front Microbiol 7: 833 DOI:10.3389/fmicb.2016.00833	Editorial: Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria	UNICA, GUF	2016
45	Malloci G, Serra G, Bosin A, Vargiu AV Computation 4: 5 DOI:10.3390/computation4010005	Extracting Conformational Ensembles of Small Molecules from Molecular Dynamics Simulations: Ampicillin As A Test Case	UNICA	2016
44	Scorciapino, M. A. et al. Future Med Chem 8, 1047–1062 (2016). DOI:10.4155/fmc-2016-0038	Exploiting the porin pathway for polar compound delivery into Gram-negative bacteria.	UNICA	2016
43	Vaas LAI, Witt G, Windshügel B, Bosin A, Serra G, Bruengger A, Winterhalter M, Gribbon P, Levy-Petelinkar CJ, Kohler M PeerJ Computer Science 2:e83 DOI:10.7717/peerj-cs.83	Electronic laboratory notebooks in a public-private-partnership	IME-SP, UNICA, JUB, BASILEA, GSK, UGE	2016
42	N. Modi, S. Ganguly, I. Bárcena-Uribarri, R. Benz, B. van den Berg and U. Kleinekathöfer Biophys. J. 109, 1429–1438 DOI:10.1016/j.bpj.2015.07.035	Structure, Dynamics, and Substrate Specificity of the OprO Porin from Pseudomonas aeruginosa	JUB, NEW	2015
41	Isabella, Vincent M.; Campbell, Arthur J.; Manchester, John; et al. CHEMISTRY & BIOLOGY 22: 535-547 DOI:10.1016/j.chembiol.2015.03.018	Toward the Rational Design of Carbapenem Uptake in Pseudomonas aeruginosa	AZ	2015
40	Vila-Farres X, Lopez-Rojas R, Pachon-Ibanez ME, Teixido M, Pachon J, Vila J, Giralt E Eur J Med Chem 101: 34-40 DOI:10.1016/j.ejmech.2015.06.016	Sequence-activity relationship, and mechanism of action of mastoparan analogues against extended-drug resistant Acinetobacter baumannii	CRESIB	2015
39	Winterhalter M, Ceccarelli M Eur J Pharm Biopharm. 95, 63-7 DOI:10.1016/j.ejpb.2015.05.006	Physical methods to quantify small antibiotic molecules uptake into Gram-negative bacteria	JUB, UNICA	2015
38	Zahn M, D'Agostino T, Eren E, Baslé A, Ceccarelli M, van den Berg B. J Mol Biol. 427:2329-39 DOI:10.1016/j.jmb.2015.03.016	Small-Molecule Transport by CarO, an Abundant Eight-Stranded ß-Barrel Outer Membrane Protein from Acinetobacter baumannii	UNICA, NEW	2015
37	Du, D., van Veen, H.W., Murakami, S., Pos, K. M. and Luisi, B. Curr. Opinion Struc. Biol. 33: 76-91 DOI:10.1016/j.sbi.2015.07.015	Structure, mechanism and cooperation of bacterial multidrug efflux transporters	GUF	2015
36	Zhou Y, Joubran C, Miller-Vedam L, Vincent I, Nayar A, Tentarelli S, Miller A Anal. Chem., 87 (7), pp 3579–3584 DOI:10.1021/ac504880r	Thinking Outside the "Bug": A Unique Assay To Measure Intracellular Drug Penetration in Gram-Negative Bacteria	AZ	2015
35	Acosta-Gutierrez S, Scorciapino M, Mariano A, Bodrenko I, and Matteo Ceccarelli J. Phys. Chem. Lett., 6 (10), pp 1807–1812 DOI:10.1021/acs.jpclett.5b00612	Filtering with Electric Field: The Case of E. coli Porins	UNICA	2015
34	Niraj Modi, Ivan Barcena Uribarri, Manjeet Bains, Roland Benz, Robert Hancock, Ulrich Kleinekathoefer ACS Chemical Biology 10: 441-51 DOI:10.1021/cb500399j	Tuning the affinity of anion binding sites in porin channels with negatively charged residues: Molecular details for OprP	JUB	2015
33	Cama J, Bajaj H, Pagliara S, Maier T, Braun Y, Winterhalter M, Keyser UF. J. Am. Chem. Soc., 137, 13836–13843 DOI:10.1021/jacs.5b08960	Quantification of Fluoroquinolone Uptake through the Outer Membrane Channel OmpF of Escherichia coli	JUB	2015
32	Gutsmann T, Heimburg T, Keyser U, Mahendran KR, Winterhalter M. Nat Protoc. 10:188-98 DOI:10.1038/nprot.2015.003	Protein reconstitution into freestanding planar lipid membranes for electrophysiological characterization	JUB	2015
31	Van den Berg B, Prathyusha Bhamidimarri S, Winterhalter M Sci. Report, 5, 11927 DOI:10.1038/srep11927	Crystal structure of a COG4313 outer membrane channel	NEW, JUB	2015
30	B. Cinquin, L. Maigre, E. Pinet, J. Chevalier, R. A. Stavenger, S. Mills, M. Réfregiers and J.-M. Pagès Sci. Rep. 5:17968 DOI:10.1038/srep17968	Microspectrometric insights on the uptake of antibiotics at the single bacterial cell level	AMU, SYN, GSK, AZ	2015
29	Bodrenko I, Bajaj H, Ruggerone P, Winterhalter M, Ceccarelli M. Analyst. 140:4820-7 DOI:10.1039/c4an02293a	Analysis of fast channel blockage: revealing substrate binding in the microsecond range	UNICA, JUB	2015
28	Weichbrodt C, Bajaj H, Baaken G, Wang J, Guinot S, Kreir M, Behrends JC, Winterhalter M, Fertig N. Analyst. 140:4874-81 DOI:10.1039/c4an02335h	Antibiotic translocation through porins studied in planar lipid bilayers using parallel platforms	NAN, JUB	2015
27	Pothula KR, Kleinekathöfer U Analyst 140(14): 4855-64 DOI:10.1039/c5an00036j	Theoretical analysis of ion conductance and gating transitions in the OpdK (OccK1) channel	JUB	2015
26	Samanta S, Scorciapino MA, Ceccarelli M Physical Chemistry Chemical Physics : PCCP 17: 23867–76 DOI:10.1039/c5cp02844b	Molecular Basis of Substrate Translocation Through the Outer Membrane Channel OprD of Pseudomonas Aeruginosa.	UNICA	2015
25	Paulen A, Gasser V, Hoegy F, Perraud Q, Pesset B, Schalk IJ, Mislin GL Org Biomol Chem 13(47): 11567-79 DOI:10.1039/c5ob01859e	Synthesis and antibiotic activity of oxazolidinone-catechol conjugates against Pseudomonas aeruginosa	CNRS	2015
24	Vaulont S, Schalk IJ Med Sci (Paris) 31(8-9): 756-63 DOI:10.1051/medsci/20153108014	Roles of bacterial and mammalian siderophores in host-pathogen interactions	CNRS	2015
23	van den Berg B, Prathyusha Bhamidimarri S, Dahyabhai Prajapati J, Kleinekathöfer U, Winterhalter M. Proc Natl Acad Sci U S A. 112:E2991-9 DOI:10.1073/pnas.1424835112	Outer-membrane translocation of bulky small molecules by passive diffusion	JUB, NEW	2015
22	Périamé M, Philippe N, Condell O, Fanning S, Pagès JM, Davin-Regli A Lett Appl Microbiol. DOI:10.1111/lam.12435	Phenotypic changes contributing to Enterobacter gergoviae biocide resistance	AMU, UCD, JUB	2015
21	Pletzer D, Braun Y, Dubiley S, Lafon C, Köhler T, Page MGP, Mourez M, Severinov K, Weingart H J Bacteriol 197:2217–222 DOI:10.1128/jb.00234-15	The Pseudomonas aeruginosa PA14 ABC Transporter NppA1A2BCD Is Required for Uptake of Peptidyl Nucleoside Antibiotics	JUB, UGE, BASILEA, SARD	2015
20	Schulz R, Vargiu AV, Ruggerone P, Kleinekathöfer U. Biomed Res Int. 487298 DOI:10.1155/2015/487298	Computational study of correlated domain motions in the AcrB efflux transporter	UNICA, JUB	2015
19	Philippe N, Maigre L, Santini S, Pinet E, Claverie JM, Davin-Regli A, Pagès JM, Masi M PLOS ONE. 2015 Sep 23;10(9):e0138828 DOI:10.1371/journal.pone.0138828	In vivo evolution of bacterial resistance in two cases of Enterobacter aerogenes infections during treatment with imipenem	AMU, JUB	2015
18	Benz R., Jones M.D., Younas F., Maier E., Modi N., Mentele R., Lottspeich F., Kleinekathöfer U., and Smit J. PLoS One DOI:10.1371/journal.pone.0143557	OmpW of Caulobacter crescentus functions as an outer membrane channel for cations	JUB	2015
17	Müller R. T., Pos K. M. Biol Chem. 396(9-10):1083-9 DOI:10.1515/hsz-2015-0150	The assembly and disassembly of the AcrAB-TolC three-component multidrug efflux pump	GUF	2015
16	Davin-Regli A, Pagès JM Front Microbiol 6:392 DOI:10.3389/fmicb.2015.00392	Enterobacter aerogenes and Enterobacter cloacae; versatile bacterial pathogens confronting antibiotic treatment	AMU	2015
15	Anes J, McCusker MP, Fanning S, Martins M Front Microbiol 6: 587 DOI:10.3389/fmicb.2015.00587	The ins and outs of RND efflux pumps in Escherichia coli	UCD	2015
14	Dreier J and Ruggerone P Front Microbiol 6: 660 DOI:10.3389/fmicb.2015.00660	Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa	BASILEA, UNICA	2015
13	Malloci, G.; Vargiu, A.V.; Serra, G.; Bosin, A.; Ruggerone, P.; Ceccarelli, M. Molecules 2015, 20, 13997-14021 DOI:10.3390/molecules200813997	A Database of Force-Field Parameters, Dynamics, and Properties of Antimicrobial Compounds	UNICA	2015
12	Bialek-Davenet S, Lavigne JP, Guyot K, Mayer N, Tournebize R, Brisse S, Leflon-Guibout V, Nicolas-Chanoine MH. J. Antimicrob. Chemother. 2015; 70: 81–88 DOI:10.1093/jac/dku340	Differential contribution of AcrAB and OqxAB efflux pumps to multidrug resistance and virulence in Klebsiella pneumonia	APHP-BUH	2015
11	Cha, H., Pos KM In: Krämer R., Ziegler C. (eds) Membrane Transport Mechanism. Springer Series in Biophysics, vol 17. Springer, Berlin, Heidelberg Chapter 9: 207-232 DOI:10.1007/978-3-642-53839-1_9	Cooperative transport mechanism and proton-coupling in the multidrug efflux transporter complex AcrAB-TolC. Membrane Transport Mechanism – 3D structure and beyond	GUF	2014
10	G.L.A. Mislin and I.J. Schalk Metallomics 6, 408-420 DOI:10.1039/c3mt00359k	Siderophore-dependent iron uptake systems as gates for antibiotic Trojan horse strategies against Pseudomonas aeruginosa	CNRS	2014
9	Baco E, Hoegy F, Schalk IJ, Mislin GL Org Biomol Chem 12(5): 749-57 DOI:10.1039/c3ob41990h	Diphenyl-benzo[1,3]dioxole-4-carboxylic acid pentafluorophenyl ester: a convenient catechol precursor in the synthesis of siderophore vectors suitable for antibiotic Trojan horse strategies	CNRS	2014
8	Cunrath O, Gasser V, Hoegy F, Reimmann C, Guillon L, Schalk IJ. Env. Microbiology 2014 DOI:10.1111/1462-2920.12544	A cell biological view of siderophore Pyochelin iron uptake pathway in Pseudomonas aeruginosa	CNRS	2014
7	Stavenger RA, Winterhalter M Sci. Transl. Med. 6:228ed7 DOI:10.1126/scitranslmed.3008605	TRANSLOCATION project: how to get good drugs into bad bugs	JUB, GSK	2014
6	Cha, H., Müller, RT, Pos, KM Antimicrob. Agents Chemother. 58:4767-4772 DOI:10.1128/aac.02733-13	Switch-loop flexibility affects transport of large drugs by the promiscuous AcrB multidrug efflux transporter	GUF	2014
5	Daniel Pletzer, Corinne Lafon, Yvonne Braun, Thilo Köhler, Malcolm G. P. Page, Michael Mourez, Helge Weingart PLOS ONE DOI:10.1371/journal.pone.0111311	High-Throughput Screening of Dipeptide Utilization Mediated by the ABC Transporter DppBCDF and its Substrate-binding Proteins DppA1-A5 in Pseudomonas aeruginosa	JUB, UGE, BASILEA, SARD	2014
4	Eicher, T, Seeger, MA, Anselmi, C, Zhou, W, Brandstätter, L, Verrey, F, Diederichs, K, Faraldo-Gómez, JD, Pos, KM eLife 3:e03145 DOI:10.7554/eLife.03145	Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump	GUF	2014
3	N. Modi, I. Bárcena-Uribarri, M. Bains, R. Benz, R.E.W. Hancock, and U. Kleinekathöfer Biochemistry 52, 5522-5532 DOI:10.1021/bi400522b	Role of the central arginine R133 towards the ion selectivity of the phosphate specific channel OprP: effects of charge and solvation	JUB	2013
2	J. Lu, N. Modi, and U. Kleinekathöfer J. Phys. Chem. B, 117 (50), pp 15966–15975 DOI:10.1021/jp408495v	Simulation of Ion Transport Through an N-acetylneuraminic Acid-inducible Membrane Channel: From Understanding to Engineering	JUB	2013
1	P. Ruggerone, S. Murakami, K. M. Pos, and A.V. Vargiu Curr. Top. Med. Chem. 13, 3079-3100 DOI:10.2174/15680266113136660220	RND Efflux Pumps: Structural Information Translated Into Function And Inhibition Mechanisms	UNICA, GUF	2013